The Cannabis Plant and the Endocannabinoid System

Cannabis Plant

The cannabis plant is made up of several chemical compounds, and these are known as cannabinoids. CBG (cannabigerol) is one of the more prominent types of cannabinoid that has been studied for its effects on the endocannabinoid system. Life Research CBG also works as an antibiotic which helps it provide a variety of different therapeutic benefits.

CBG can also help to:

  • Relieve pain
  • Increase appetite
  • Reduce inflammation
  • Combat cancerous cells
  • Enhance moods
  • Promote sleep, and
  • Fight infection

There are also other different types of cannabinoids that have been discovered: Tetrahydrocannabinol (also known as THC), cannabidiol (CBD), cannabinol (CBN) and others. Cannabinoids are produced by the cannabis plant and they work to inhibit the activity of an enzyme known as CB1. This is an important mechanism for cannabinoid signaling, but it does have its limitations.

There is an interesting fact about the effects of cannabinoids on the endocannabinoid system. When cannabinoids or other compounds bind to CB1 receptors, they actually:

  • Block the binding of endocannabinoids and they therefore act as an antagonist (this can be confusing because antagonists are typically considered to be a negative event).
  • Rundown levels of the endocannabinoids anandamide and 2-arachidonoylglycerol (2-AG) in the brain. This is also considered to be an undesirable effect because endocannabinoids are thought to work in a more subtle way, and running down their levels at least in the short-term could work against this.
  • Have the ability to activate vanilloid receptors (which are different from cannabinoid receptors). The function of the vanilloid receptor is a bit of a mystery at this point.
  • The discovery of CBG more than 45 years ago was considered to be an important discovery for researchers and scientists who study cannabis biology. The idea behind the initial discovery was a simple one. The authors of the study noted that there was a link between the degradation of CBG and several adverse effects in rats. When CBG was present in their diets, the results were not very favorable compared to when it was not present.

Researchers have been doing studies on how various cannabinoids like full spectrum spagyrics CBG tincture 1000mg CBG and other compounds can affect healthy cells and our endocannabinoid system. While CBG Products has not been a major focus of these studies, there are some revealing pieces of information that have been uncovered. For example, when CBG was tested on cells that were positive for human papillomavirus (HPV), it was discovered that CBG could inhibit the growth of these cells. In a similar way, it was found that CBG could reduce the chance of breast cancer and other types of cancers as well.

In one study, CBG was shown to have some anti-epileptic effects. This could be a very important discovery because seizures can be fatal in some cases. The human brain is actually made up of a similar collection of compounds as cannabis is, which may make it easier for CBG to interact with and treat epilepsy.

The Body’s Endocannabinoid System

Endocannabinoids play a crucial role in regulating our moods, appetite, and metabolism. They are also responsible for the release of dopamine from the human brain. This process is what creates our sense of pleasure and well-being when we want to experience happiness or pleasure.

In this post, we discuss the endocannabinoid system (ECS), how it’s affected by cannabis use, and why so many people are turning to marijuana as a treatment for chronic health problems like arthritis pain or PTSD.

Cannabinoids, or simply cannabis, have been studied for centuries. Studies dating back to the 1980s indicate cannabis interacts with specific receptors in the brain — even more specifically with the central nervous system. The endocannabinoid system explains how these chemical compounds trigger reactions in our body and lead to effects like increased appetite and pain relief. This system is made of two primary types of cannabinoid receptors, CB1 and CB2, which are found throughout our neural pathways. CB1 receptors are found on neurons and glial cells and CB2 receptors are found throughout the brain.

With over 120 identified cannabinoids, we are still learning about the various ways these compounds affect our health and emotions. However, as more research is being done, we are discovering that a person’s experiences with THC may actually be more important than their genetics or even what strain they are consuming.

For example, researchers have found that a person’s genetic makeup determines much of their risk of developing depression and anxiety, while the amount of THC consumed actually plays a less significant role. This is because all cannabinoids in cannabis are stored in fat tissue and not the brain. So, it seems that simply taking THC doesn’t provide any benefits for your mental health. In fact, one well-known study found that smoking cannabis up to three times a day didn’t have any significant impact on symptoms of anxiety or depression.

Not surprisingly, there are people who turn to marijuana for relief from chronic pain. But, when it comes to chronic pain, many people don’t realize that cannabis is a proven treatment that works. In fact, research shows that around 50 percent of chronic pain patients using opioids like Vicodin or OxyContin experience withdrawal symptoms when attempting to stop their use. However, only ten percent of those patients go on to become addicted. Marijuana, on the other hand, is not physically addictive and not associated with the same withdrawal symptoms as those substances.

Pain relief is just one benefit of medicinal cannabis. In addition to chronic pain, many people are turning to marijuana for things like appetite stimulation and mood stability. For example, marijuana has been used to treat conditions like fibromyalgia (a condition that causes widespread muscle pain), multiple sclerosis (a neurological disease that damages nerve cells), arthritis, migraines, and insomnia.

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