Managing type 2 diabetes effectively often involves finding the right medication to help control blood glucose levels. Two popular options are Invokana and Farxiga.
But which one is more effective? In this article, we’ll compare Invokana vs Farxiga to understand their benefits, risks, and patient reviews clearly.
So, take a moment to read on and discover which of these medications may be a better option for you.
Mechanism of Action
Invokana and Farxiga belong to a class of medications known as sodium-glucose cotransporter 2 (SGLT2) inhibitors. They work by blocking the reabsorption of glucose in the kidneys, which can lead to increased glucose excretion in urine.
This mechanism helps to lower blood sugar levels and prevent hyperglycemia, a common symptom of type 2 diabetes. It also promotes weight loss as excess glucose is eliminated from the body.
When it comes to glucose control, both medications are equally effective. However, some differences between the two may influence a patient’s decision.
Effectiveness
When it comes to effectiveness, both Invokana and Farxiga are effective in improving glycemic control in patients with type 2 diabetes. These medications can reduce fasting blood glucose levels by around 30 mg/dL and HbA1c levels by 0.5-0.7%.
However, Invokana may be more effective in reducing HbA1c levels compared to Farxiga. This can be attributed to the fact that Invokana has a higher potency and longer duration of action. This means that it stays in the body for a longer period.
Cardiovascular Benefits
One of the major concerns for people with type 2 diabetes is the increased risk of cardiovascular diseases. This is where Invokana stands out. This is because it has been shown to have significant cardiovascular benefits.
In a large clinical trial, Invokana was found to reduce the risk of major adverse cardiovascular events (MACE) by 14%, compared to a placebo. It also showed a 38% reduction in the risk of cardiovascular death and a 39% reduction in the risk of hospitalization for heart failure.
On the other hand, Farxiga has not been shown to have significant cardiovascular benefits. However, it is still considered safe and effective for managing type 2 diabetes.
Weight Loss Potential
As mentioned earlier, both Invokana and Farxiga can promote weight loss due to their mechanisms of action. However, conflicting findings have been made on which one is more effective.
Farxiga may lead to greater weight loss compared to Invokana. However, some say there are no significant differences between the two medications.
Ultimately, the amount of weight loss may vary from person to person and depend on other factors such as diet and exercise. With diabetes management, focusing on overall health is important rather than just weight loss.
Safety Profile
Both Invokana and Farxiga have similar safety profiles, with the most common side effects being urinary tract infections and genital infections. However, there are some differences in the potential risks associated with each medication.
Invokana has been linked to an increased risk of lower limb amputation. Farxiga has been associated with an increased risk of bone fractures. It is important to discuss any potential risks with your doctor before starting either of these medications.
Renal Function
People with type 2 diabetes are at a higher risk of developing kidney disease. Therefore, it is important to consider the impact of these medications on renal function.
Invokana and Farxiga can improve renal outcomes in people with type 2 diabetes. However, Invokana is more effective in reducing the progression of chronic kidney disease.
Contraindications and Precautions
Both Invokana and Farxiga have similar contraindications and precautions. They are not recommended for use in pregnant or breastfeeding women.
They should also be used with caution in patients with a history of kidney disease. This goes the same for those taking certain medications that may interact with them.
It is important to discuss any potential contraindications or precautions with your doctor before starting treatment with either of these medications. This will help ensure the safety and effectiveness of your treatment plan.
Drug Interactions
Both Invokana and Farxiga can interact with certain medications. They can potentially lead to adverse effects or reduced effectiveness. It is important to inform your doctor about any other medications you are taking, including over-the-counter drugs and supplements.
Some common medications that may interact with Invokana and Farxiga include:
- diuretics
- blood pressure medications
- insulin
Your doctor may need to adjust your dosage or monitor you closely for any potential interactions.
Cost and Insurance Coverage
One important consideration when choosing between Invokana and Farxiga may be the cost and insurance coverage. Both medications can be expensive, with Farxiga generally being slightly more affordable.
However, the actual cost may vary depending on your insurance coverage and any available financial assistance programs. It is worth discussing this with your doctor or pharmacist to find the most affordable option.
And if you are looking for an affordable Farxiga cost or Invokana cost, there are always online pharmacy options that may offer discounted prices or manufacturer coupons. This can help make these medications more accessible for those struggling with the cost.
Patient Preferences and Lifestyle Factors
When deciding between Invokana and Farxiga, it is important to consider your preferences and lifestyle factors. For example, if you have a fear of needles, you may prefer taking Farxiga as it is available in pill form.
You should also consider any other health conditions or medications you manage. Your doctor can help you weigh the pros and cons of each medication and make an informed decision based on your individual needs.
Moreover, it’s important to remember that these medications are not a substitute for healthy lifestyle choices. Take note that the following are crucial:
- eating a balanced diet
- exercising regularly
- managing stress
All these help in managing type 2 diabetes effectively.
Weigh Before Choosing Between Invokana vs Farxiga
Both Invokana and Farxiga are effective medications for managing type 2 diabetes. However, there are certain differences between Invokana vs Farxiga too.
When choosing between these two options, discussing with your doctor and considering certain factors is important. Your doctor can help you make an informed decision based on your individual needs to effectively manage your type 2 diabetes.
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Disclaimer: This article contains sponsored marketing content. It is intended for promotional purposes and should not be considered as an endorsement or recommendation by our website. Readers are encouraged to conduct their own research and exercise their own judgment before making any decisions based on the information provided in this article.
